招聘簡(jiǎn)介：

　　·舊金山加利福尼亞大學(xué)

　　·地點(diǎn)：CA舊金山

　　·工作編號(hào)：7056469

　　·發(fā)布日期：2019年3月14日

　　·申請(qǐng)截止日期：2019年5月14日

　　職位描述

　　我們正尋求任命一位具有放射化學(xué)或有機(jī)化學(xué)背景的博士后研究助理，利用新的活細(xì)胞示蹤劑進(jìn)行研究，以追蹤人類感染。這項(xiàng)工作將在加州大學(xué)舊金山分校最先進(jìn)的中國(guó)盆地和任務(wù)灣校區(qū)的大衛(wèi)·威爾遜實(shí)驗(yàn)室進(jìn)行。該研究的重點(diǎn)是開發(fā)一些有希望快速轉(zhuǎn)化為臨床實(shí)踐的放射性示蹤劑（見 https://www-nature-com.ucsf.idm.oclc.org/articles/s41598-017-08415-x and https://pubs.acs.org/doi/abs/10.1021/acsinfecdis.8b00061).這些示蹤劑也將是研究模型感染中活細(xì)菌代謝狀態(tài)的極好工具。我們還開發(fā)了尖端技術(shù)，通過超極化13C核磁共振光譜（https://pubs.acs.org/doi/abs/10.1021/acsinfeccdis.7b00234）研究細(xì)菌代謝，我們計(jì)劃在我們的努力中部署。

　　英文原文：

　　·         University of California, San Francisco

　　·         Location: San Francisco , CA

　　·         Job Number: 7056469

　　·         Posting Date: Mar 14, 2019

　　·         Application Deadline: May 14, 2019

　　Job Description

　　We are seeking to appoint a Postdoctoral Research Associate with a background in radiochemistry or organic chemistry to undertake research using new live-cell tracers to track infections in humans. The work will be undertaken in the laboratory of David Wilson at the state-of-the-art China Basin and Mission Bay campuses of UCSF. The focus of the research is on the development of several radiotracers that have promise for rapid translation into clinical practice (see for example https://www-nature-com.ucsf.idm.oclc.org/articles/s41598-017-08415-x and https://pubs.acs.org/doi/abs/10.1021/acsinfecdis.8b00061). Such tracers will also be excellent tools to study the metabolic states of living bacteria in model infections. We have also developed cutting edge techniques to study bacterial metabolism via hyperpolarized 13C NMR spectroscopy (https://pubs.acs.org/doi/abs/10.1021/acsinfecdis.7b00234), which we plan to deploy in our efforts.

　　Applicants should hold a Ph.D. or M.D., or be near completion of their degree, in a relevant subject area. The applicant should have relevant research experience in synthetic chemistry and biologic validation of small molecules, and have a proven research track record. The applicant should also be highly motivated with exceptional communications skills and the ability to work with a dynamic team. Preferred skills would be prior experience with animal models and experience with the tools of chemical biology.

　　This full-time post is fully funded by the NIH and DARPA.

　　Interested applicants should submit 1) a curriculum vitae, 2) a brief statement of research interests and 3) a list of three references. Please send inquiries to David Wilson (david.m.wilson@ucsf.edu)

　　This is a full-time, one-year appointment with the possibility of renewal based on the availability of funding, ongoing operational needs and satisfactory performance. The University of California, San Francisco is an affirmative action/equal opportunity employer with a strong institutional commitment to the achievement of diversity among its faculty, staff, and students.

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