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意大利羅馬歐洲分子生物學(xué)實(shí)驗(yàn)室博士后職位

時(shí)間:2019-03-28來源:中國博士人才網(wǎng) 作者:佚名

 招聘簡介:

  關(guān)于團(tuán)隊(duì)/工作

  Boulard和Gross團(tuán)隊(duì)正在尋找一位對表觀基因組學(xué)和轉(zhuǎn)錄組學(xué)有濃厚興趣的生物信息學(xué)博士后研究員,以領(lǐng)導(dǎo)對表觀遺傳學(xué)和神經(jīng)科學(xué)接口項(xiàng)目框架中生成的大規(guī)模“OMIC”數(shù)據(jù)集的分析。

  本項(xiàng)目結(jié)合了Boulard和Gross兩組在染色質(zhì)生物學(xué)和神經(jīng)回路方面的專業(yè)知識,分別探索轉(zhuǎn)錄因子和大腦表觀基因組之間的細(xì)胞類型特異性相互作用。成功的申請者將加入一個(gè)由分子生物學(xué)家、生物化學(xué)家和神經(jīng)科學(xué)家組成的合作團(tuán)隊(duì)。

  你的角色

  指定人員將負(fù)責(zé)大規(guī)模表觀基因組和轉(zhuǎn)錄組數(shù)據(jù)集的計(jì)算分析,包括:

  1)開發(fā)分析Cutnrun和DAP Seq數(shù)據(jù)集的方法和管道,以及

  2)集成、比較、挖掘和可視化“OMIC”數(shù)據(jù)集。

  該職位涉及與濕實(shí)驗(yàn)室科學(xué)家合作開發(fā)和實(shí)施定制分析。

  英文原文:

  About the team/job

  The Boulard and Gross Groups are seeking to recruit a Postdoctoral Fellow in bioinformatics with a strong interest in epigenomics and transcriptomics to lead the analysis of large-scale “omic” datasets generated in the frame of a project at the interface of epigenetics and neuroscience.

  This project combines the expertise of the Boulard and Gross groups in chromatin biology and neural circuits, respectively, to explore the cell-type specific interplay between transcription factors and the brain epigenome. The successful applicant will be embedded in a collaborative team of molecular biologists, biochemists, and neuroscientists.

  Your role

  The person appointed will be responsible for the computational analyses of large-scale epigenomic and transcriptomic datasets, including:

  1) developing methods and pipelines to analyze CutnRun and DAP-seq data sets, and

  2) integrating, comparing, mining, and visualizing “omic” data sets.

  The position involves the development and the implementation of custom analyses in collaboration with wet-lab scientists.

  You have

  ·         PhD degree in Bioinformatics, Computer Science, Mathematics, or related fields.

  ·         Solid skillset and experience in bioinformatics:

  o    Excellent knowledge of R and biostatistics

  o    Experience and proven track record in handling NGS datasets and developing analysis pipelines

  ·         Outstanding interpersonal and communication skills are essential

  You might also have

  ·         Experience with Unix-based environment and high-performance computing cluster environment is not required, but would be considered an advantage.

  ·         Experience in motif discovery is not required, but would be considered an advantage.

  Why join us

  The European Molecular Biology Laboratory (EMBL) is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits. Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.

  What else do I need to know

  EMBL is one of the highest ranked scientific research organizations in the world. We are an international, innovative and interdisciplinary laboratory with more than 1600 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton, Hamburg, Grenoble and Rome. The Neurobiology and Epigenetics Unit at EMBL Rome studies mammalian physiology from the molecular to the systems level using the laboratory mouse as a model system. We take advantage of a full range of core facilities, including bioinformatics services and a high-performance computing cluster.

  For more information, please see our website at www.embl.it.

  To apply please submit a cover letter clearly stating your motivation and future research interests/plans and a CV with at least two referees through our online system at www.embl.it/jobs.

  Applications are welcome from all nationalities, appointment will be based on merit alone.

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