英國(guó)MRC倫敦醫(yī)學(xué)科學(xué)院2024年招聘博士后（疾病的分子機(jī)制）

英國(guó)醫(yī)學(xué)研究理事會(huì)(Medical Research Council，簡(jiǎn)稱(chēng)MRC)成立于1913年，隸屬于英國(guó)研究理事會(huì)，是一個(gè)由英國(guó)公共資金建立的國(guó)家級(jí)政府機(jī)構(gòu)，是英國(guó)七大國(guó)家級(jí)研究理事會(huì)之一，其宗旨是資助為改善人們健康狀況而開(kāi)展的醫(yī)學(xué)研究。

MRC Postdoctoral Research Scientist in Molecular Mechanisms of Disease – Genomic Variation and Disease Group – LMS 2483

MRC London Institute of Medical Sciences

MRC Postdoctoral Research Scientist in Molecular Mechanisms of Disease

Genomic Variation and Disease Group

(3 Years fixed term)

Salary: £39,375 plus London allowances (£3,913 & £1,472) per annum

London, UK

The Genomic Variation and Disease Group works at the intersection of medical genetics, bioinformatics, and molecular biology to explore the mechanisms underlying human diseases. The group uses CRISPR/Cas9 genome editing and synthetic genomics for mouse or human genome rewriting to model disease- causing chromosomal structural variants (SVs) and study their functional consequences. Our challenge is understanding how this type of genomic variation affects molecular and cellular processes to influence organismal phenotypes.

We are looking for a talented postdoctoral scientist with a background in molecular biology to join our team. As a key member, you will be part of our collaborative effort to explore novel SV-associated disease mechanisms. Your work will involve generating in vitro (cellular differentiation) and/or in vivo mouse models to investigate the molecular consequences of SVs impacting the noncoding genome.

At our newly established lab, we are committed to creating a welcoming and supportive environment where people of all backgrounds can thrive. We value diversity and collaboration and focus on conducting cutting-edge basic and translational science. We provide extensive on-the-job training as needed for the projects. At the LMS, we also offer excellent mentoring and support to help you reach your career goals. As a post holder, you will have the opportunity to work with an extensive network of collaborators, attend scientific conferences, and publish the results of your work in leading journals.

This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successful applicant is likely to be eligible to apply.

Final appointment will be subject to pre-employment screening

Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly installments. The Training Allowance increases to £1,300 in year two and £1,800 in the third year.

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