Helmholtz Zentrum München

Job Title:  Postdoctoral scientist m/f in a research project to phenotypically and epigenetically analyse the effects of parentally acquired diabetes on the proge
Job Number:  4014783 (Ref.#. 2014-2453)
Date Posted:  08/20/2014
Application Deadline: Open Until Filled
Job Description

The Helmholtz Zentrum München in Munich, Germany, is member of one of the leading research associations in Europe - the Helmholtz Association of German Research Centers. The aim of our research is to proactively detect health risks involving humans and the environment, decoding the mechanisms of pathogenesis and developing concepts for prevention and therapy.

The Institute of Experimental Genetics is looking for a Postdoctoral scientist (m/f) in a research project to phenotypically and epigenetically analyse the effects of parentally acquired diabetes on the progeny in an animal model 2014/2453

Job Description
A major goal in this project within the framework of the French-German Diabetes Academy is to begin to dissect
the contribution of epigenetic inheritance versus the effect of the maternal environment to the predisposition of deve-loping a diabetic phenotype in the offspring.
• Use of an established mouse model for acquired diabetes
• Phenotypic analyses of progeny from diabetic mothers, in particular, with
regards to classical diabetes parameters
• Molecular analyses (including metabolomics, proteomics and
transcriptomics)
of selected organs
• Analyses of maternal effects on the epigenome of the progeny (DNA
methylation, histone modifications and chromatin accessibility)

Your Qualifications
• Candidates are highly motivated scientists with a degree in biology,
molecular biology, biotechnology, biochemistry, or in a similar faculty and
have an excellent doctorate
• Previous knowledge in molecular and/or genetic methods, in particular in
next generation sequencing, in metabolic disorders, as well as experience
or interest in working with mouse models will be to your advantage
• Above-average commitment and the ability to work in a team, as well as
analytic thinking, independent working, very good computer skills,
knowledge of statistical methods and excellent knowledge of written and
spoken English are necessary prerequisites

Our Offer
• Working in an innovative, well- equipped and scientifi-cally stimulating
surrounding
• Perform research in an internationally leading and highly attractive
academic environment
• Perform independent research in an interdisciplinary team with exceptional
facilities for phenotyping, muta-genesis, transcriptomics, proteomics and
metabolomics and within international cooperations.
• Further training opportunities
• Initial short-term employment contract for two years with a standard public
service salary (TV EntgO Bund EG 13)

The Helmholtz Zentrum München as holder of the Bavarian Advancement of Women Prize and of the Total E-Quality Certificate is striving to increase the overall proportion of women on its staff and thus expressly urges qualified women to apply.

Theresa Schwarzfischer
E-mail: t.schwarzfischer@helmholtz-muenchen.de

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit
und Umwelt (GmbH)
Institute for Biological and Medical Imaging
Ingolstädter Landstr. 1
D-85764 Neuherberg/München, Germany
 
 
Contact:  Theresa Schwarzfischer
Institute for Biological and Medical Imaging
Helmholtz Zentrum München
Ingolstädter Landstr. 1
Neuherberg-München,  85764
Germany
Email: t.schwarzfischer@helmholtz-muenchen.de
Employer's Web Site:  Visit employer's website
亥姆霍茲慕尼黑中心
 
職位名稱：在一個(gè)研究項(xiàng)目，博士后科學(xué)家，男/女，以表型和表觀遺傳學(xué)分析腸胃后天糖尿病對(duì)PROGE的影響
發(fā)布日期：二○一四年八月二十〇日
報(bào)名截止日期：不限滿為止

 
職位描述

亥姆霍茲慕尼黑中心位于德國(guó)慕尼黑，是全球領(lǐng)先的研究團(tuán)體在歐洲的一個(gè)成員 - 德國(guó)研究中心的亥姆霍茲聯(lián)合會(huì)。我們研究的目的是要主動(dòng)地檢測(cè)涉及人類和環(huán)境的，解碼發(fā)病機(jī)制和開(kāi)發(fā)的概念對(duì)于預(yù)防和治療的健康風(fēng)險(xiǎn)。

實(shí)驗(yàn)遺傳學(xué)研究所正在尋找一個(gè)博士后科學(xué)家（男/女）的一個(gè)研究項(xiàng)目，表型和表觀遺傳學(xué)分析在動(dòng)物模型二千四百五十三分之二千〇十四腸胃收購(gòu)合并糖尿病對(duì)后代的影響

職位描述
在法國(guó)，德國(guó)糖尿病學(xué)會(huì)的框架內(nèi)該項(xiàng)目的主要目標(biāo)是，開(kāi)始解剖
表觀遺傳與母體環(huán)境對(duì)的傾向影響的貢獻(xiàn)德韋-loping的后代糖尿病的表型。
•利用已建立的小鼠模型獲得的糖尿病
•表型分析從糖尿病母親的后代，尤其是與
關(guān)于古典糖尿病參數(shù)
•分子分析（包括代謝組學(xué)，蛋白質(zhì)組學(xué)和
轉(zhuǎn)錄）
選擇器官
•對(duì)后代的表觀基因組母體效應(yīng)分析（DNA
甲基化，組蛋白修飾和染色質(zhì)可訪問(wèn)）

你的資歷
•考生都非常積極的科學(xué)家，主修生物學(xué)，
分子生物學(xué)，生物技術(shù)，生物化學(xué)，或者類似的教師和
有一個(gè)很好的博士學(xué)位
•先前知識(shí)在分子和/或遺傳方法，特別是在
下一代測(cè)序，在代謝性疾病，以及經(jīng)驗(yàn)
或與小鼠模型的工作權(quán)益將是你的優(yōu)勢(shì)
•高于平均水平的承諾，并在一個(gè)團(tuán)隊(duì)中工作，以及能力
分析思考，獨(dú)立工作，很不錯(cuò)的電腦技能，
統(tǒng)計(jì)方法的知識(shí)和優(yōu)秀的書(shū)面知識(shí)，
英語(yǔ)口語(yǔ)是必要的先決條件

我們的報(bào)價(jià)
•工作中的一個(gè)創(chuàng)新，裝備精良和scientifi，刺激美云
周邊
•在國(guó)際上處于領(lǐng)先和極具吸引力進(jìn)行研究
學(xué)術(shù)環(huán)境
•在一個(gè)跨學(xué)科的團(tuán)隊(duì)，卓越的執(zhí)行自主研發(fā)
為表型，墓塔，成因，轉(zhuǎn)錄組學(xué)，蛋白質(zhì)組學(xué)和設(shè)施
代謝組學(xué)和國(guó)際合作范圍內(nèi)。
•進(jìn)一步培訓(xùn)的機(jī)會(huì)
兩年•初始的短期雇傭合同與標(biāo)準(zhǔn)的公共
服務(wù)人員薪金（電視EntgO外灘EG13）

亥姆霍茲慕尼黑中心的總電子質(zhì)量認(rèn)證的巴伐利亞提高婦女獎(jiǎng)和持有人正在努力增加?jì)D女在其工作人員的整體比例，從而明確敦促合格的婦女申請(qǐng)。

特里薩Schwarzfischer
電子郵箱：t.schwarzfischer@helmholtz-muenchen.de

亥姆霍茲慕尼黑中心
德意志FORSCHUNGSZENTRUM獻(xiàn)給Gesundheit
UND UMWELT（有限公司）
研究所生物和醫(yī)學(xué)成像
IngolstädterLandstr。 1
D-85764 Neuherberg市/慕尼黑，德國(guó)
  
 
聯(lián)系方式：特里薩Schwarzfischer
研究所生物和醫(yī)學(xué)成像
亥姆霍茲慕尼黑中心
IngolstädterLandstr。 1
Neuherberg市 - 慕尼黑，85764
德國(guó)
電子郵件：t.schwarzfischer@helmholtz-muenchen.de

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