招聘簡介：

　　在馬克斯普朗克醫(yī)學(xué)研究所，馬克斯普朗克科學(xué)促進會的84個研究所之一，物理學(xué)家，化學(xué)家和生物學(xué)家創(chuàng)造了與生命長期相關(guān)的知識

　　和基礎(chǔ)醫(yī)學(xué)。

　　在海德堡馬克斯普朗克醫(yī)學(xué)研究所的化學(xué)生物學(xué)系（Kai Johnsson教授）可以獲得博士后職位（2年或更長時間）。

　　博士后職位（m / f / d）（代碼編號08/2019）

　　該項目的目標(biāo)是開發(fā)針對適合疼痛治療的新型傷害感受器選擇性蛋白質(zhì)靶標(biāo)的先導(dǎo)化合物。成功的候選者將開發(fā)用于從編碼的組合文庫（噬菌體展示，DNA展示）中選擇特異性結(jié)合復(fù)雜蛋白質(zhì)靶標(biāo)的小分子的新方法。通過這些方法產(chǎn)生的分子隨后將在創(chuàng)新的疾病相關(guān)生物學(xué)測定中進行評估。該項目是與哈佛醫(yī)學(xué)院和波士頓兒童醫(yī)院的團隊長期合作的一部分。

　　優(yōu)先考慮具有編碼組合庫（噬菌體展示或DNA展示）的先前經(jīng)驗的候選人，或蛋白質(zhì)工程和化學(xué)生物學(xué)領(lǐng)域的候選人。

　　英文原文：

　　At the Max Planck Institute for Medical Research, one of the 84 institutes of the Max Planck Society for the Advancement of Science, physicists, chemists and biologists create knowledge of long-term relevance to life

　　and basic medical sciences.

　　Postdoctoral positions (2 years or longer) are available at the Department of Chemical Biology (Prof. Kai Johnsson) of the Max Planck Institute of Medical Research in Heidelberg.

　　Postdoctoral Positions (m/f/d) (Code number 08/2019)

　　The goal of the project is the development of lead compounds against new nociceptor-selective protein targets suitable for pain therapy. The successful candidates will develop novel approaches for the selection of small molecules from encoded combinatorial libraries (phage display, DNA display) that specifically bind to complex protein targets. Molecules generated through these approaches will subsequently be evaluated in innovative, disease-relevant biological assays. The project is part of a long-term collaboration with groups from Harvard Medical School and Boston Children’s Hospital.

　　Priority will be given to candidates with previous experiences with encoded combinatorial libraries (phage display or DNA display), or in the fields of protein engineering and chemical biology.

　　The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. The Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds. A daycare center for children is located near the institute.

　　For further inquiries please contact Prof. Kai Johnsson at johnsson@mr.mpg.de.

　　For general questions, please contact Ms. Sabrina Giacalone or Mrs. Fabienne Höfer-Elfner (+49 6221 486- 305/311) from human resources.

　　Please submit your application, including a cover letter (explaining background and motivation), your CV, and addresses of two references via e-mail as a single PDF file with the above reference preferably until June 30, 2019 to jobs@vw.mpimf-heidelberg.mpg.de.

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