招聘簡介：

　　關(guān)于團(tuán)隊(duì)/工作

　　Gross和Boulard團(tuán)隊(duì)正在尋找一位才華橫溢的博士后研究員加入一個(gè)跨學(xué)科項(xiàng)目，研究DNA甲基化在大腦基因表達(dá)控制中的作用。這個(gè)項(xiàng)目結(jié)合了Gross和Boulard兩組在神經(jīng)回路和表觀遺傳學(xué)方面的專業(yè)知識，來理解染色質(zhì)修飾是如何形成細(xì)胞類型特異性控制大腦基因表達(dá)的。

　　你的角色

　　領(lǐng)導(dǎo)一個(gè)項(xiàng)目，分析細(xì)胞類型特異性病毒介導(dǎo)基因和神經(jīng)活動干擾后小鼠大腦中的基因表達(dá)變化；開發(fā)和實(shí)施先進(jìn)的分子遺傳學(xué)工具來實(shí)施該項(xiàng)目。

　　英文原文:

　　About the team/job

　　The Gross and Boulard Groups are looking for a highly talented postdoctoral researcher to join an interdisciplinary project on the role of DNA methylation in brain gene expression control. This project combines the expertise of the Gross and Boulard groups in neural circuits and epigenetics, respectively, to understand how chromatin modifications are able to shape cell-type specific control of gene expression in the brain.

　　Your role

　　Lead a project to profile and analyse gene expression changes in mouse brain following cell-type specific viral-mediated gene and neural activity perturbations; develop and implement cutting-edge molecular genetic tools to carry out the project.

　　You have

　　A PhD and a proven track record in molecular biology (DNA cloning, isolation of cells from tissue, immunoprecipitation, flow cytometry) and in vivo animal experimentation (husbandry, genotyping, surgery, stereotactic injection). You have a demonstrated ability in interpersonal communication and collaboration. You will demonstrate strong initiative, have the ability to work independently to drive the project forward, and be keen to work in a collaborative, international environment.

　　You might also have

　　Experience in computational analysis of sequencing data (data quality control and preparation, R programming, gene network and enrichment analysis).

　　Why join us

　　The European Molecular Biology Laboratory (EMBL) is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization with a collegial and family-friendly working environment. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits.

　　What else do I need to know

　　EMBL is one of the highest ranked scientific research organizations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK), Barcelona (Spain), and Rome (Italy). The Neurobiology and Epigenetics Unit at EMBL Rome studies mammalian physiology from the molecular to the systems level using the laboratory mouse as a model system. We take advantage of a full range of core facilities as well as close institutional links with other EMBL sites.

　　For more information, please see our website at www.embl.it.

　　To apply please submit a cover letter clearly stating your motivation and future research interests/plans and a CV with at least two referees through our online system

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