招聘信息：

　　德國癌癥研究中心是德國最大的生物醫(yī)學研究機構(gòu)。我們擁有約3,000名員工，在癌癥研究領域開展了廣泛的科學計劃。

　　氧化還原法規(guī)司正在尋找博士后科學家（Ref-No。2019-0053）

　　描述：

　　我們正在尋找一名博士后研究員加入DKFZ的氧化還原法規(guī)司，提供高度互動和協(xié)作的科學環(huán)境。我們研究了代謝衍生的氧化劑在信號轉(zhuǎn)導中的作用以及正常和腫瘤細胞中蛋白質(zhì)氧化還原調(diào)節(jié)和應激適應的原理。我們采用廣泛的技術(shù)，從活細胞成像和基因組工程到蛋白質(zhì)組學和生物化學。有關(guān)詳細信息，請參閱我們的網(wǎng)頁http://www.dkfz.de/en/redoxregulation/。

　　該職位是ERC資助項目的一部分，該項目旨在系統(tǒng)地發(fā)現(xiàn)，剖析，監(jiān)測和操縱蛋白質(zhì)氧化還原相互作用，為氧化還原信號傳導提供特異性和效率。將采用遺傳篩選，氧化還原蛋白質(zhì)組學和轉(zhuǎn)錄分析的組合來解開氧化還原信號傳導途徑的組織，它們的靶蛋白及其對基因調(diào)節(jié)的功能影響。該項目預計將產(chǎn)生對特定分子鏈的基本見解，通過這些分子鏈，活性氧，氮和硫物種將代謝變化與調(diào)節(jié)恢復力和健康跨度的細胞和生物適應相結(jié)合。該位置被指定用于哺乳動物細胞。

　　你的個人資料：

　　擁有生物學/生命科學或生物化學/化學博士學位，分子生物學，細胞生物學和/或生物化學的高級知識，以及豐富的實驗室經(jīng)驗。需要氧化還原生物學的背景，但不是必需的。

　　申請人應具有高度的自我激勵能力，能夠獨立開展研究項目以及合作。優(yōu)秀的書面和口頭英語口語至關(guān)重要。

　　請在一份PDF文件中提交您的申請，其中包括簡歷，一份說明研究和職業(yè)興趣的信函，中學和大學證書的成績單，預計可用日期以及2-3份推薦信。

　　該職位限于2年，有可能延長。

　　該職位原則上可以是兼職。

　　欲了解更多信息，請聯(lián)系PD Dr. Tobias Dick，電話：+49 6221 42-2320。

　　德國癌癥研究中心致力于提高女科學家的比例，并鼓勵女性申請者申請。在具有相同資質(zhì)和資格的候選人中，將優(yōu)先考慮殘疾人。

　　要申請職位，請使用我們的在線申請門戶網(wǎng)站（www.dkfz.de）。

　　我們要求您理解我們無法退回通過郵寄發(fā)送給我們的申請文件（Deutsches Krebsforschungszentrum，Personalabteilung，Im Neuenheimer Feld 280,69120 Heidelberg），并且我們不接受通過電子郵件提交的申請。對由此造成的任何不便，我們深表歉意。

　　英文原文：

　　The German Cancer Research Center is the largest biomedical research institution in Germany. With approximately 3,000 employees, we operate an extensive scientific program in the field of cancer research.

　　The Division of Redox Regulation is seeking a

　　Postdoctoral Scientist

　　(Ref-No. 2019-0053)

　　Description:

　　We are seeking a postdoctoral researcher to join the Division of Redox Regulation at DKFZ, offering a highly interactive and collaborative scientific environment. We study the role of metabolically derived oxidants as messengers in signal transduction and the principles of protein redox regulation and stress adaptation in normal and tumor cells. We employ a broad range of techniques, ranging from live-cell imaging and genome engineering to proteomics and biochemistry. For more information please see our web page http://www.dkfz.de/en/redoxregulation/.

　　The position is part of an ERC-funded project that aims to systematically uncover, dissect, monitor and manipulate protein redox interactions that give specificity and efficiency to redox signaling. A combination of genetic screening, redox proteomics and transcription profiling will be employed to unravel the organization of redox signaling pathways, their target proteins und their functional impact on gene regulation. The project is expected to yield fundamental insights into the specific molecular links by which reactive oxygen, nitrogen and sulfur species couple changes in metabolism to cellular and organismal adaptations regulating resilience and health span. The position is designated for work with mammalian cells.

　　Your profile:

　　A PhD in biology / life sciences or biochemistry / chemistry, advanced knowledge of molecular biology, cell biology and/or biochemistry, and substantial laboratory experience are required. A background in redox biology is desired, but not essential.

　　The applicant should be highly self-motivated and be able to pursue research projects independently as well as in collaborations. An excellent written and oral command of English is essential.

　　Please submit your application in a single PDF file with CV, a letter stating research and career interests, transcripts of secondary school and university certificates, expected availability date, and 2-3 letters of reference.

　　The position is limited to 2 years with the possibility of prolongation.

　　The position can in principle be part-time.

　　For further information please contact PD Dr. Tobias Dick, phone +49 6221 42-2320.

　　The German Cancer Research Center is committed to increase the percentage of female scientists and encourages female applicants to apply. Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

　　To apply for a position please use our online application portal (www.dkfz.de).

　　We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.

為防止簡歷投遞丟失請抄送一份至：boshijob@126.com（郵件標題格式：應聘職位名稱+姓名+學歷+專業(yè)+中國博士人才網(wǎng)）