招聘簡(jiǎn)介:
·愛因斯坦醫(yī)學(xué)院
·地點(diǎn):紐約
·工作編號(hào):7056649
·發(fā)布日期:2019年3月28日
職位描述
美國(guó)國(guó)立衛(wèi)生研究院資助的涉及濕工作臺(tái)和OMIC肺部水平發(fā)現(xiàn)和驗(yàn)證的轉(zhuǎn)化人類研究所需的具有強(qiáng)大分子遺傳學(xué)和實(shí)質(zhì)性信息學(xué)技能的博士后研究員。我們正在探索“正常”肺的體細(xì)胞突變、DNA甲基體和轉(zhuǎn)錄組特征,因?yàn)樗鼈兣c衰老和致癌有關(guān)。將采用獨(dú)特的基于CRISPR的技術(shù),以及選定的研究員,對(duì)肺中的主要甲基體點(diǎn)擊進(jìn)行功能驗(yàn)證。實(shí)驗(yàn)室有一個(gè)特殊的,臨床注釋的人類肺和替代組織收集,允許發(fā)展肺癌風(fēng)險(xiǎn)的非侵入性生物標(biāo)志物作為一個(gè)平行相關(guān)的持續(xù)活動(dòng)。
英文原文:
· Albert Einstein College of Medicine
· Location: , NY
· Job Number: 7056649
· Posting Date: Mar 28, 2019
Job Description
Post-doctoral fellow with strong molecular genetics and substantive informatics skills needed for NIH-funded translational human studies involving wet bench and omic's level discovery and validation in the lung. We are exploring somatic mutationome, DNA methylome, and transcriptome features in “normal” lung, as they relate to aging and carcinogenesis. Functional validation of key methylome hits in the lung will be pursued, using unique CRISPR-based technology as well by the selected fellow. The lab has an exceptional, clinically-annotated human lung and surrogate tissue collection, permitting the development of non-invasive biomarkers of lung cancer risk as a parallel related ongoing activity.
• Ph.D. degree required
To apply, please email your CV and a short cover letter summarizing your experience, along with the contact information of three references to Dr. Simon Spivack at simon.spivack@einstein.yu.edu and Karen.milian@einstein.yu.edu
The Albert Einstein College of Medicine is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.
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