深圳灣實(shí)驗(yàn)室位于粵港澳大灣區(qū)核心引擎，是深圳新建立的生命健康科學(xué)研究機(jī)構(gòu)，由詹啟敏院士擔(dān)任實(shí)驗(yàn)室主任，林建華教授擔(dān)任特別顧問(wèn)，吳云東院士任實(shí)驗(yàn)室常務(wù)副主任。實(shí)驗(yàn)室由北京大學(xué)深圳研究生院與相關(guān)單位共同舉辦，協(xié)同粵港澳大灣區(qū)健康科學(xué)領(lǐng)域具有研究基礎(chǔ)和應(yīng)用優(yōu)勢(shì)的單位合作共建。深圳灣實(shí)驗(yàn)室將堅(jiān)持“立足深圳、問(wèn)題導(dǎo)向、匯聚人才、支撐發(fā)展”的發(fā)展理念，建設(shè)世界一流生命科學(xué)和生物醫(yī)藥領(lǐng)域的學(xué)術(shù)研究中心。

分子生理學(xué)研究所重點(diǎn)研究領(lǐng)域包括（1）分子生物學(xué)基本原理如基因表達(dá)調(diào)控的動(dòng)態(tài)過(guò)程及功能、DNA損傷修復(fù)機(jī)制等，（2）分子生物學(xué)技術(shù)如基因編輯、分子動(dòng)態(tài)標(biāo)記、基因治療等，（3）基本的生理學(xué)問(wèn)題如傳染病感染機(jī)制、神經(jīng)免疫調(diào)節(jié)、睡眠機(jī)理等。核心研究方向?yàn)橹匾�生物學(xué)過(guò)程的分子生物學(xué)機(jī)理和先進(jìn)分子生物學(xué)技術(shù)的開(kāi)發(fā)及應(yīng)用。

分子生理學(xué)研究所將借鑒全球頂級(jí)生物學(xué)研究機(jī)構(gòu)的成功經(jīng)驗(yàn)，結(jié)合國(guó)內(nèi)科研改革方向，通過(guò)在研究所建立合理的科研運(yùn)作機(jī)制、打造頂尖的科研平臺(tái)和研究資源、引進(jìn)一流的科學(xué)家團(tuán)隊(duì)、與國(guó)內(nèi)外頂級(jí)科研單位建立長(zhǎng)期穩(wěn)定的合作，將研究所建設(shè)為國(guó)際一流的研發(fā)機(jī)構(gòu)。

分子生理學(xué)研究所可共享以下研究平臺(tái)：

分子成像平臺(tái)

將搭載超分辨成像系統(tǒng)、活細(xì)胞工作平臺(tái)、常用共聚焦顯微鏡，提供最為先進(jìn)的成像技術(shù)并進(jìn)行新型成像技術(shù)的開(kāi)發(fā)。

分子文庫(kù)中心

將構(gòu)建全基因組篩選用的基因文庫(kù)，建立常用病毒包裝系統(tǒng)，為進(jìn)一步的高通量篩選、分子進(jìn)化、基因治療等研究提供支撐。

動(dòng)物中心

第一期將建設(shè)500m2左右的SPF級(jí)別鼠房，容納小鼠籠位2000個(gè)左右，保證相關(guān)動(dòng)物實(shí)驗(yàn)的順利開(kāi)展。隨著相關(guān)研究課題的開(kāi)展，將建設(shè)8000m2的動(dòng)物飼養(yǎng)空間，大小鼠籠位各12000籠。

高通量篩選平臺(tái)

將搭載全自動(dòng)高通量篩選設(shè)備，可在細(xì)胞、線(xiàn)蟲(chóng)、斑馬魚(yú)等系統(tǒng)中進(jìn)行小規(guī)�；�合物篩選、高通量遺傳篩選（siRNAs、 shRNAs、 cDNAs、CRISPR）以及高通量篩選數(shù)據(jù)的處理等，為科學(xué)家提供全方位的篩選實(shí)驗(yàn)設(shè)計(jì)、技術(shù)指導(dǎo)和數(shù)據(jù)分析。

基因組學(xué)中心

將搭建高通量測(cè)序系統(tǒng)和生物信息學(xué)分析平臺(tái)，是研究基因轉(zhuǎn)錄調(diào)控等重要問(wèn)題的基礎(chǔ)。

蛋白質(zhì)組學(xué)平臺(tái)

將搭建多種蛋白質(zhì)質(zhì)譜分析系統(tǒng)，為科學(xué)家提供先進(jìn)的基于高分辨質(zhì)譜技術(shù)的蛋白質(zhì)組學(xué)技術(shù)支撐。

轉(zhuǎn)基因動(dòng)物中心

將提供基本的轉(zhuǎn)基因動(dòng)物構(gòu)建、動(dòng)物凈化、胚胎凍存等服務(wù)。

一、招聘對(duì)象：

海內(nèi)外知名院校及科研機(jī)構(gòu)中，從事生命科學(xué)前沿研究的各層次人才。崗位包括首席科學(xué)家，資深研究員（tenured），特聘研究員（預(yù)聘，tenure-track）。

二、應(yīng)聘條件：

【資深研究職位】：主要包括 首席科學(xué)家，資深研究員（tenured）

具有博士學(xué)位，應(yīng)在海內(nèi)外知名高校、科研院所擔(dān)任副教授、副研究員以上或相當(dāng)職務(wù)。

【預(yù)聘研究職位】：主要包括 特聘研究員（預(yù)聘，tenure-track）

具有博士學(xué)位；應(yīng)聘人學(xué)術(shù)水平和資歷應(yīng)達(dá)到擔(dān)任海內(nèi)外知名高校助理教授或副教授職務(wù)的相應(yīng)標(biāo)準(zhǔn)；首聘期5-6年，后通過(guò)評(píng)估決定是否獲得長(zhǎng)聘崗位（tenured）。

三、薪酬福利與其他待遇：

1. 薪酬和福利待遇

提供具有國(guó)際競(jìng)爭(zhēng)力的薪酬待遇；協(xié)助申請(qǐng)深圳市人才安居房或高層次人才補(bǔ)貼。

2. 科研保障

獨(dú)立實(shí)驗(yàn)和辦公空間；參照國(guó)際一流研究院所提供啟動(dòng)經(jīng)費(fèi)，根據(jù)申請(qǐng)人研究計(jì)劃面議；協(xié)助申請(qǐng)各類(lèi)人才經(jīng)費(fèi)；可配研究助手，研究生名額優(yōu)先。

四、應(yīng)聘材料及聯(lián)系方式：

應(yīng)聘材料：

1 個(gè)人中英文簡(jiǎn)歷

2 自薦信

3發(fā)表學(xué)術(shù)成果列表

4 研究總結(jié)與研究計(jì)劃（含研究經(jīng)費(fèi)預(yù)算）

5 三名推薦人姓名及聯(lián)系方式

將上述材料發(fā)送至深圳灣實(shí)驗(yàn)室人事部招聘郵箱：HR_PI@szbl.ac.cn，郵件標(biāo)題注明：應(yīng)聘崗位+本人姓名+所學(xué)專(zhuān)業(yè) 。

如需了解更多深圳灣實(shí)驗(yàn)室信息，請(qǐng)瀏覽官方網(wǎng)站： www.szbl.ac.cn

深圳灣實(shí)驗(yàn)室分子生理學(xué)研究所為全球?qū)W術(shù)人才提供公平的申請(qǐng)機(jī)會(huì)，招聘常年進(jìn)行中，誠(chéng)邀海內(nèi)外各層次杰出學(xué)術(shù)人才加盟！

Recruitment of Faculty for Institute of Molecular Physiology

of Shenzhen Bay Laboratory

About the Shenzhen Bay Laboratory（SZBL）

The Shenzhen Bay Laboratory (SZBL) is a newly established institution focus on health sciences research, located in the heart of the China Great Bay Area. It was launched by the Peking University and Shenzhen city with an initial budget of $2 billion USD/5yr. SZBL aspires to be a world-class research institution and intellectual destination dedicated to understanding the fundamental biology underlying health and diseases while spurring solutions to the grand challenges confronting our world’s population and human well-being. The mission of the SZBL is to create a new research model to boost the health sciences and nurture the innovation-oriented biotechnology industry.

About the Institute of Molecular Physiology of SZBL

The Institute of Molecular Physiology focuses research in two major areas - the molecular mechanism in important biological process and the development and application of advanced techniques in molecular biology. The former will primarily focus on the replication, repair, expression and regulation of genes and other basic molecular biological events as such and associated mechanisms during the significant processes of genetic proliferation, aging and lesion. The latter carries out research and application of molecular biotechniques such as molecular evolution, gene editing, molecular marker for detection and gene therapy. Research will be both basic and applied, covering up four major aspects including gene repair and duplication, regulation of gene expression, molecular mechanisms of infectious diseases, techniques of molecular biology. Though these research and discovery, the Institute will effectively unite research from both basic and applied to facilitate the translation of research results.

The Institute of Molecular Physiology can share the following research platforms:

- Molecular Imaging Platform

It will be equipped with a super-resolution imaging system, a living cell working platform, and confocal microscopes to provide the most advanced imaging technology and develop new imaging technologies.

- Gene Library

A gene library for genome-wide screening will be constructed, and virus packaging systems will be established to provide support for further research on high-throughput screening, molecular evolution, and gene therapy.

- Animal Center

An SPF-level animal house of about 500m2 will first be constructed to accommodate about 2,000 mouse cages to facilitate relevant animal experiments. Further construction of about 8000m2 will provide animal breeding spaces for 12,000 cages of mouse and rat, respectively.

- High-throughput Screening Platform

It will be equipped with a full-automatic high-throughput screening device, which can perform small-scale compound screening, high-throughput genetic screening (siRNAs,shRNAs,cDNAs,CRISPR) and processing of high-throughput screening data in cells, nematodes, zebrafish and other systems, providing comprehensive screening experiment design, technical guidance and data analysis in scientific research.

- Genomics Center

A high-throughput sequencing system and a bioinformatics analysis platform will be built, which will be vital and fundamental for scientific research such as gene transcription regulation.

- Proteomics Platform

A variety of protein mass spectrometry systems will be established to provide advanced proteomics technology based on high-resolution mass spectrometry for scientific research.

- Transgenic Animal Center

It will provide a variety of scientific service, including transgenic animal construction, animal purification, embryo cryopreservation and so on.

Whom we’re looking for

Institute of Molecular Physiology of SZBL strives to deliver cutting-edge technology to the global scientific community through worldwide innovation and collaboration with experts and we are looking for the brightest minds to help us achieve our goals.

We are looking to fill multiple faculty positions at all ranks. Applicants should have a doctoral degree in biology, chemistry, pharmacy and medicine or closely related fields. Postdoctoral experience is required for a junior position (Assistant Professor). Applicants for senior positions are expected to have a demonstrated publication and funding record indicative of a leading scientist.

The applicant can identify which of the above areas is his or her primary areas. Review of applications will start April 2019, but positions will remain open until filled.

What is offered

Startup package and salaries will be competitive at an international level. A package of fringe benefits that include health and retirement benefits. The SZBL will also help applicants apply for national and local talent programs.

Your Application

The Institute of Molecular Physiology of SZBL is an equal opportunity employer and welcomes applicants from all sections of the community.

Required Application documents:

1.    Curriculum vitae

2.    Cover letter

3.    Lists of publications and research funding

4.    Research summary and proposal

5.    Name and contact details of 3 references

Contact:

Please send the application documents by email attachment to HR_PI@szbl.ac.cn

Email subject: the title of the position for which you are applying.

For more details on SZBL and our research, please visit our website: www.szbl.ac.cn

Email content: please include your contact information, name, telephone number, and any dates on which you would be unavailable for an interview. Upon request, applications will be considered confidentially.

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